The stable microbubble test to predict CPAP success

The stable microbubble test (SMT) performed on gastric aspirate in the first hour of life was prospectively studied in 68 infants less than 30 weeks gestation placed on CPAP immediately after birth. The diagnostic test accuracy of the SMT was determined using success of CPAP as the reference standard.  A cut-off value of eight or more bubbles per cu mm had a sensitivity of 53% and specificity of 100%. The stable microbubble test may help identify very preterm infants that are likely to succeed on CPAP and not need intubation.

Stable microbubble test for determining CPAP success in very preterm infants. Bhatia et al, 2013