The ideal admission temperature in preterm infants < 33 weeks of gestation

Submitted by: Krithika Lingappan, MD

A retrospective observational study of nearly 10,000 neonates neonates  <33 weeks of gestation from 29 NICUs in the Canadian Neonatal Network sought to estimate the admission temperature associated with lowest rates of adverse outcomes. The primary outcome was a composite adverse outcome defined as mortality or any of the following: severe neurological injury, severe retinopathy of prematurity, necrotizing enterocolitis, bronchopulmonary dysplasia, or nosocomial infection. There was a U-shaped relationship between the admission temperature and the primary outcome. The admission temperature at which the rate of the composite outcome was lowest was 36.8°C (95% CI, 36.7°C-37.0°C).

Association between admission temperature and mortality and major morbidity in preterm infants born at fewer than 33 weeks’ gestation.  Lyu et al, 2015.