Lung-protective respiratory support in preterm infants

Lung injury in preterm infants receiving respiratory support can be decreased by avoiding: (1) Atelectrauma by promoting alveolar stability, (2) Volutrauma by limiting tidal volume to prevent alveolar overdistension, and (3) Oxitrauma by minimizing oxygen toxicity by improving ventilation-perfusion matching. A review article from Switzerland traces the progress of respiratory support in preterm infants, describes how our understanding of BPD has evolved over the years, and explains current concepts about how best to protect the lungs of preterm infants with non-invasive ventilation strategies and oxygen saturation targeting.

The journey toward lung-protective respiratory support in preterm infants. Berger et al, 2013.