Eliminating delays in antibiotic administration

A single-center report describes the results of a quality improvement project aiming to shorten the interval between an antibiotic order and actual administration of the antibiotic to less than two hours in neonates with suspected late-onset sepsis. Through iterative cycles and using education, standardization, streamlining of workflow and computerized order entry, the team shortened the antibiotic administration times from a median of 138 minutes to 75 minutes, and also decreased the variation in practice.

Antibiotic timing with suspected late-onset sepsis. Bissinger et al, 2013