EEG characteristics that predict outcome in HIE

A systematic review of studies in term neonates with hypoxic-ischemic encephalopathy assessed the diagnostic accuracy of background features of the EEG in identifying future neurodevelopmental outcome. Data were extracted from 31 eligible studies and meta-analyzed. Definitions for burst suppression, low voltage, and flat tracing varied across the studies, as did the timing and duration of the EEG studies. The following EEG features had a relatively high area under the receiver operating characteristic curve: burst suppression (sensitivity 0.87; specificity 0.82), low voltage (sensitivity 0.92; specificity 0.99), and flat trace (sensitivity 0.78; specificity 0.99).

EEG background features that predict outcome in term HIE. Awal et al, 2015