Diazoxide for hyperinsulinemic hypoglycemia

A single-center randomized trial in small-for gestational age infants with a gestation of 32 weeks or greater who had hyperinsulinemic hypoglycemia compared the effects of diazoxide with placebo. Infants treated with diazoxide had a lower: median time to achieve hypoglycemia control (40 vs 71.5 hours, p=0.015), duration of intravenous fluids (114 vs 164 hours, p=0.04), and time to achieve full feeds (74 vs 124 hours, p=0.02) No apparent adverse effects were noted..

Diazoxide for small for gestational age infants with hyperinsulinemic hypoglycemia. Balachandran et al, 2018