Category: Glucose

Continuous glucose monitoring – better glucose control?

A single center randomized trial from Italy in very-low-birth-weight infants compared the titration of the glucose infusion rate using continuous glucose monitoring versus periodic glucose measurement using bedside glucometers (with the continuous values hidden from clinicians). In both arms of…

Dextrose gel to manage hypoglycemia

A single-center observational (pre-post) study reported outcomes of treatment of neonatal hypoglycemia before and after a practice change was implemented. Compared to hypoglycemic infants treated with feed supplementation alone (prior to the practice change), infants treated with dextrose gel in addition to feed supplementation…

Treatment of hypoglycemia with dextrose gel

A single-center randomized trial of babies greater than 35 weeks gestation at high risk for hypoglycemia, who had blood glucose less than 47 mg/dl in the first 48 hours of life compared treatment with 40% dextrose gel massaged into the…

Glucose monitoring in neonates – do not trust the glucometer

Blood glucose is ideally measured in the laboratory, with methods that use glucose oxidase, hexokinase or glucose dehydrogenase reactions. In practice, it is measured using point-of-care (POC) glucose meters because they provide a quick result with a small sample of…

Hyperglycemia in preterm infants: should we use insulin for tighter glucose control?

A randomized study from New Zealand of hyperglycemic preterm infants compared the use of insulin to achieve tight glycemic control (blood glucose target 72 – 108 mg/dl, 4 – 6 mmol/L)  to more restrictive usage of insulin (target blood glucose range  144…

Hypoglycemia in at-risk babies

In this study from New Zealand, low glucose levels developed in over half of babies > 35 weeks gestation who had risk factors for hypoglycemia. Almost 20% had severe hypoglycemia and almost 20% had more than one episode of hypoglycemia.…