Category: Breast milk

Donor breast milk vs formula – a randomized trial

In a double-blind multicenter trial very-low birth weight infants with inadequate supply of their mother’s own milk were randomly assigned to receive either donor breast milk with bovine fortifier or formula (for 90 days or until discharge). There were no…

A summary of evidence on nutrition

An expert group has published a summary of the existing evidence on multiple aspects of neonatal nutrition and identified research priorities in this field. A couple of excerpts from this summary: “Current nutrient recommendations for preterm infants are based on…

Increased protein intake and neurodevelopmental outcomes

A prospective cohort study compared neurodevelopmental outcomes in extremely-low-birth-weight infants (less than 1000 grams birth weight), before and after a regimen of increased protein intake (according to international consensus recommendations) was introduced. The Bayley-III was used for assessment. A significant improvement in early growth…

Gastric residuals in preterm infants

A randomized trial in preterm infants compared outcomes in infants 24 – 32 weeks gestation in whom gastric residuals were routinely checked prior to every feed versus those in whom residuals were not checked. An algorithm guided all other aspects…

Educational intervention to extend breastfeeding

A randomized trial of over five hundred black and Latina mothers studied the effects of a post-delivery culturally-tailored educational intervention on the duration of breast feeding. The intervention group mothers received an in-hospital educational session with a social worker, educational…

Bovine lactoferrin supplementation to reduce NEC

A multicenter randomized trial in very low birth weight infants studied the use of routine supplementation of enteral feeds with bovine lactoferrin (BLF) and probiotics (lactobacillus rhamnosus GG, LGG). Infants were randomly assigned to one of three arms in the…

The new paradigm of NICU care

A commentary argues that for too long we have thought of newborns as isolated organisms. In reality, neonates are dependent on their family for biopscyhosocial support that the medical system cannot substitute for. Over time the paradigm of neonatal care…

Iodine supplementation of infants versus their mothers

In parts of the world where iodised salt is not routinely used, iodine deficiency in infants can be corrected by giving supplemental iodine either to breastfeeding mothers (indirect infant supplementation) or to the infants (direct infant supplementation). A randomized controlled…

Bed-sharing on maternity wards and risk of death or near-death

A case series of fifteen healthy newborn infants who died or three who nearly died when sharing a bed with the mother on a maternity ward found that accidental suffocation was the most likely cause of these incidents. These cases…

Purchasing human milk on the internet

Breast milk can be purchased directly through special websites without human milk bank involvement. Investigators from Ohio obtained around 100 breast milk samples from two such sites and cultured the milk. Almost three quarters of them had either Gram negative…

Exclusive human milk diet versus cows milk formula and fortifier

A multicenter randomized trial in extremely preterm infants compared a feeding regimen based exclusively on human milk (donor breast milk with fortifier derived from human milk) to one using preterm formula and fortifier derived from cows milk. Infants were eligible…